Seattle’s secondary took a bruising Week 5 as Riq Woolen departed with a concussion, leaving Nehemiah Pritchett to hold down the corner spot while Devon Witherspoon and Julian Love sat. Baker Mayfield attacked Seattle’s thin coverage for 379 yards and two touchdowns, and a late Sam Darnold performance capped the heartbreak with a 38-35 loss. Derick Hall also missed action, compounding the depth issues as Seattle looks toward Week 6 against Jacksonville with hopes for healthier bodies in the secondary.

The looming question for fantasy managers: how thin is Seattle’s CB depth, and who steps up when Witherspoon and Love return? The Jaguars test the unit immediately, so attention shifts to who fills roles, how much Seattle relies on rookies, and whether the offense can keep pace behind the evolving injury picture.

Week 5 pits Seattle against Tampa Bay in a high-stakes NFC showdown, but both sides ride notable inactive lists. Seattle lists seven absences—DeMarcus Lawrence, Julian Love, Devon Witherspoon, Jared Ivey, Josh Jones, Cody White, Nick Kallerup—while Tampa Bay sits Mike Evans, Jamel Dean, Bucky Irving, Christian Izien, and Benjamin Morrison. With these starters out, fantasy managers should recalibrate expectations and consider how backups could lift or limit the box score in today’s tilt.

Backups stepping in across both teams will shape assignments, targets, and defensive matchups, altering DFS values and ceiling floors. The absence of top playmakers forces coaches to lean on depth and scheme, which can create upside for opportunistic players and more volatility for starters who rely on these absences to drive production.